Improving Intestinal Barrier Function in Sepsis by Partially Hydrolysed Guar Gum via the Suppression of the NF-κB/MLCK Pathway

Author:

Tang ZhaoxiaORCID,Zhu Yanping,Hu Xiaoguang,Lui Kayin,Li Shuhe,Song Xiaodong,Cai Changjie,Guan Xiangdong

Funder

Wu Jieping Medical Foundation

Guangdong Clinical Research Center for Critical Care Medicine

Sun Yat sen University Clinical Research Program 5010

Publisher

Springer Science and Business Media LLC

Reference56 articles.

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2. Singer, M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J. D., Coopersmith, C. M., Hotchkiss, R. S., Levy, M. M., Marshall, J. C., Martin, G. S., Opal, S. M., Rubenfeld, G. D., van der Poll, T., Vincent, J. L., & Angus, D. C. (2016). The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA, 315, 801–810.

3. De Backer, D., Deutschman, C. S., Hellman, J., Myatra, S. N., Ostermann, M., Prescott, H. C., Talmor, D., Antonelli, M., Pontes Azevedo, L. C., Bauer, S. R., Kissoon, N., Loeches, I. M., Nunnally, M., Tissieres, P., Vieillard-Baron, A., & Coopersmith, C. M. (2024). Surviving sepsis campaign research priorities 2023. Critical Care Medicine, 52, 268–296.

4. Rudd, K. E., Johnson, S. C., Agesa, K. M., Shackelford, K. A., Tsoi, D., Kievlan, D. R., Colombara, D. V., Ikuta, K. S., Kissoon, N., Finfer, S., Fleischmann-Struzek, C., Machado, F. R., Reinhart, K. K., Rowan, K., Seymour, C. W., Watson, R. S., West, T. E., Marinho, F., Hay, S. I., … Naghavi, M. (2020). Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study. Lancet (London, England), 395, 200–211.

5. Dellinger, R. P., Levy, M. M., Rhodes, A., Annane, D., Gerlach, H., Opal, S. M., Sevransky, J. E., Sprung, C. L., Douglas, I. S., Jaeschke, R., Osborn, T. M., Nunnally, M. E., Townsend, S. R., Reinhart, K., Kleinpell, R. M., Angus, D. C., Deutschman, C. S., Machado, F. R., Rubenfeld, G. D., … Surviving Sepsis Campaign Guidelines Committee including the Pediatric, S. (2013). Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2012. Critical Care Medicine, 41, 580–637.

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