Post-stroke DHA Treatment Protects Against Acute Ischemic Brain Injury by Skewing Macrophage Polarity Toward the M2 Phenotype-Reference-Cited by-同舟云学术

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Post-stroke DHA Treatment Protects Against Acute Ischemic Brain Injury by Skewing Macrophage Polarity Toward the M2 Phenotype

Published:2018-09-10 Issue:6 Volume:9 Page:669-680
ISSN:1868-4483
Container-title:Translational Stroke Research
language:en
Short-container-title:Transl. Stroke Res.

Author:

Cai Wei,Liu Sanxin,Hu Mengyan,Sun Xiaobo,Qiu Wei,Zheng Songguo,Hu Xiaoming,Lu Zhengqi^ORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Clinical Neurology,General Neuroscience

Link

http://link.springer.com/article/10.1007/s12975-018-0662-7/fulltext.html

Reference48 articles.

1. Zhao H, Garton T, Keep RF, Hua Y, Xi G. Microglia/macrophage polarization after experimental intracerebral hemorrhage. Transl Stroke Res. 2015;6:407–9.

2. Jiang X, Pu H, Hu X, Wei Z, Hong D, Zhang W, et al. A post-stroke therapeutic regimen with omega-3 polyunsaturated fatty acids that promotes white matter integrity and beneficial microglial responses after cerebral ischemia. Transl Stroke Res. 2016;7:548–61.

3. Pu H, Jiang X, Hu X, Xia J, Hong D, Zhang W, et al. Delayed docosahexaenoic acid treatment combined with dietary supplementation of omega-3 fatty acids promotes long-term neurovascular restoration after ischemic stroke. Transl Stroke Res. 2016;7:521–34.

4. Zhang M, Wang S, Mao L, Leak RK, Shi Y, Zhang W, et al. Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1. J Neurosci. 2014;34:1903–15.

5. Chen S, Zhang H, Pu H, et al. n-3 PUFA supplementation benefits microglial responses to myelin pathology. Sci Rep. 2014;4:7458.

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