Author:
Chen Danyang,Zhao Zhixian,Zhang Shenglun,Chen Shiling,Wu Xuan,Shi Jian,Liu Na,Pan Chao,Tang Yingxin,Meng Cai,Zhao Xingwei,Tao Bo,Liu Wenjie,Chen Diansheng,Ding Han,Zhang Ping,Tang Zhouping
Abstract
AbstractIntracerebral hemorrhage (ICH) is the most serious form of stroke and has limited available therapeutic options. As knowledge on ICH rapidly develops, cutting-edge techniques in the fields of surgical robots, regenerative medicine, and neurorehabilitation may revolutionize ICH treatment. However, these new advances still must be translated into clinical practice. In this review, we examined several emerging therapeutic strategies and their major challenges in managing ICH, with a particular focus on innovative therapies involving robot-assisted minimally invasive surgery, stem cell transplantation, in situ neuronal reprogramming, and brain-computer interfaces. Despite the limited expansion of the drug armamentarium for ICH over the past few decades, the judicious selection of more efficacious therapeutic modalities and the exploration of multimodal combination therapies represent opportunities to improve patient prognoses after ICH.
Funder
Research Fund of Tongji Hospital
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC