Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway-Reference-Cited by-同舟云学术

Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway

Published:2017-12-23 Issue:5 Volume:9 Page:515-529
ISSN:1868-4483
Container-title:Translational Stroke Research
language:en
Short-container-title:Transl. Stroke Res.

Author:

Chen Hansen,Guan Binghe,Chen Xi,Chen Xingmiao,Li Caiming,Qiu Jinhua,Yang Dan,Liu Ke Jian,Qi Suhua,Shen Jiangang^ORCID

Funder

Hong Kong General Research Fund

Health and Medical Research Fund, Hong Kong SAR

Areas of Excellence Scheme, RGC, Hong Kong SAR

Shenzhen Basic Research Plan Project.

National Natural Science Foundation of China (CN)

Natural Science Foundation of the Jiangsu Higher Education Institutions of China

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Neurology (clinical),General Neuroscience

Link

http://link.springer.com/article/10.1007/s12975-017-0598-3/fulltext.html

Reference74 articles.

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3. Cheng NT, Kim AS. Intravenous thrombolysis for acute ischemic stroke within 3 hours versus between 3 and 4.5 hours of symptom onset. Neurohospitalist. 2015;5(3):101–9. https://doi.org/10.1177/1941874415583116 .

4. Kanazawa M, Takahashi T, Nishizawa M, Shimohata T. Therapeutic strategies to attenuate hemorrhagic transformation after tissue plasminogen activator treatment for acute ischemic stroke. J Atheroscler Thromb. 2017;24(3):240–53. https://doi.org/10.5551/jat.RV16006 .

5. Lees KR, Bluhmki E, Von Kummer R, Brott TG, Toni D, Grotta JC, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010;375(9727):1695–703. https://doi.org/10.1016/S0140-6736(10)60491-6 .

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