Melatonin decreases IRF-3 protein expression in the gastrocnemius muscle, reduces IL-1β and LPS plasma concentrations, and improves the lipid profile in rats with apical periodontitis fed on a high-fat diet
Author:
Funder
São Paulo Research Foundation, FAPESP
Publisher
Springer Science and Business Media LLC
Subject
General Dentistry
Link
https://link.springer.com/content/pdf/10.1007/s10266-022-00782-w.pdf
Reference41 articles.
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2. Stassen IG, Hommez GM, De Bruyn H, De Moor RJ. The relation between apical periodontitis and root-filled teeth in patients with periodontal treatment need. Int Endod J. 2006;39(4):299–308. https://doi.org/10.1111/j.1365-2591.2006.01098.x.
3. Sasaki H, Hirai K, Martins CM, Furusho H, Battaglino R, Hashimoto K. Interrelationship between periapical lesion and systemic metabolic disorders. Curr Pharm Des. 2016;22(15):2204–15.
4. Moreira AP, Texeira TF, Ferreira AB, Peluzio MC, Alfenas RC. Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia. Br J Nutr. 2012;108(5):801–9. https://doi.org/10.1017/S0007114512001213.
5. Chuffa L, Fioruci-Fontanelli BA, Mendes LO, Ferreira SFR, Martinez M, Fávaro WJ, et al. Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer. BMC Cancer. 2015. https://doi.org/10.1186/s12885-015-1032-4.
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1. Integrating network pharmacology and experimental evaluation to explore the complementary therapeutic effect and mechanism of melatonin in periodontitis;Heliyon;2024-06
2. Modulatory influence of melatonin on apical periodontitis in Wistar rats fed a high-fat diet;Archives of Oral Biology;2023-09
3. Efficacy Of Supplementary Melatonin as Adjunct to Surgical Periodontal Therapy on Periodontal Parameters: A Pilot Study;Journal of Population Therapeutics and Clinical Pharmacology;2023-01-01
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