Current molecular biomarkers evaluation in gastric/gastroesophageal junction adenocarcinoma: pathologist does matter

Author:

Businello Gianluca,Angerilli Valentina,Lonardi Sara,Bergamo Francesca,Valmasoni Michele,Farinati Fabio,Savarino Edoardo,Spolverato Gaya,Fassan MatteoORCID

Abstract

AbstractThe comprehensive molecular characterization of gastric and gastroesophageal junction adenocarcinomas has led to the improvement of targeted and more effective treatments. As a result, several biomarkers have been introduced into clinical practice and the implementation of innovative diagnostic tools is under study. Such assessments are mainly based on the evaluation of limited biopsy material in clinical practice. In this setting, the pathologist represents a key player in the selection of patients facilitating precision medicine approaches.

Funder

Associazione Italiana per la Ricerca sul Cancro

Regione del Veneto

Università degli Studi di Padova

Publisher

Springer Science and Business Media LLC

Subject

Surgery

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