Establishment of stable mouse/human-human hybrid cell lines producing large amounts of anti-tetanus human monoclonal antibodies with high neutralizing activity

Author:

Kamei M.,Hashizume S.,Sugimoto N.,Ozutsumi K.,Matsuda M.

Publisher

Springer Science and Business Media LLC

Subject

Epidemiology

Reference33 articles.

1. AleshkinV.A., BorisovaV.N., PonomaryovaA.M. and PopkovM.Y.U. (1989): Production of homologous tetanus antitoxin from commercial ?-globulin preparations. - In: Proceedings of the 8th International Conference on Tetanus. G. Nisticò, B. Bizzini, B. Bytchenko and R. Triau (eds.) - Pythagora Press, Rome-Milan, pp. 285?290.

2. BoydJ.E., HastingsI., FarzadZ., JamesK. and McClellandD.B.L. (1984):Experiences in the production of human monoclonal antibodies to tetanus toxoid. - Develop. Biol. Standard. 57: 93?98.

3. EbisawaI., MatsuhashiC., YamamotoA., KurosuY. and OtsukaT. (1981): Clinical experiences in the use of intravenously injectable tetanus-immune human gamma globulin in TIG(i). - Kansenshogaku Zasshi (J Jpn Assoc Infect Dis) 55: 92?98 (in Japanese).

4. GigliottiF. and InselR.A. (1982): Protective human hybridoma antibody to tetanus toxin. - J. Clin. Invest. 70: 1306?1309.

5. GigliottiF., SmithL. and InselR.A. (1984): Reproducible production of protective human monoclonal antibodes by fusion of peripheral blood lymphocytes with a mouse myeloma cell line. - J. Infect. Dis. 149: 43?47.

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