Overview of Role of the Immune System in the Pathogenesis of Inflammatory Bowel Disease

Author:

MacDonald Thomas T.,Monteleone Giovanni

Publisher

Springer New York

Reference67 articles.

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2. Mullin GE, Lazenby AJ, Harris ML et al. Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn’s disease but not ulcerative colitis. Gastroenterology 1992; 102:1620–1627.

3. Breese E, Braegger CP, Corrigan CJ et al. Interleukin-2-and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa. Immunology 1993; 78:127–131.

4. Fuss IJ, Neurath M, Boirivant M et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 1996; 157:1261–1270.

5. Monteleone G, Biancone L, Marasco R et al. Interleukin 12 is expressed and actively released by Crohn’s disease intestinal lamina propria mononuclear cells. Gastroenterology 1997; 112:1169–1178.

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