Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites-Reference-Cited by-同舟云学术

Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites

Published:2016 Issue: Volume: Page:249-262
ISSN:1866-3370
Container-title:Neuropharmacology of New Psychoactive Substances (NPS)
language:
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Author:

Tai Sherrica,Fantegrossi William E.

Publisher

Springer International Publishing

Link

http://link.springer.com/content/pdf/10.1007/7854_2016_60

Reference75 articles.

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3. Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR (2000) Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding. Drug Alcohol Depend 60:133–140

4. Brents LK, Gallus-Zawada A, Radominska-Pandya A, Vasiljevik T, Prisinzano TE, Fantegrossi WE, Moran JH, Prather PL (2012) Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. Biochem Pharmacol 83:952–961

5. Brents LK, Reichard EE, Zimmerman SM, Moran JH, Fantegrossi WE, Prather PL (2011) Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity. PLoS One 6:e21917

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