Enhanced production of anti-PD1 antibody in CHO cells through transient co-transfection with anti-apoptotic genes Bcl-x L and Mcl-1-Reference-Cited by-同舟云学术

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Enhanced production of anti-PD1 antibody in CHO cells through transient co-transfection with anti-apoptotic genes Bcl-x L and Mcl-1

Published:2018-01-25 Issue:5 Volume:41 Page:633-640
ISSN:1615-7591
Container-title:Bioprocess and Biosystems Engineering
language:en
Short-container-title:Bioprocess Biosyst Eng

Author:

Zhang Xinyu,Han Lei,Zong Huifang,Ding Kai,Yuan Yuan,Bai Jingyi,Zhou Yuexian,Zhang Baohong,Zhu Jianwei

Funder

Natural Science Foundation of Shanghai

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Bioengineering,Biotechnology

Link

http://link.springer.com/article/10.1007/s00449-018-1898-z/fulltext.html

Reference46 articles.

1. Zhu J (2012) Mammalian cell protein expression for biopharmaceutical production. Biotechnol Adv 30:1158–1170

2. Birch JR, Onakunle Y (2005) Biopharmaceutical proteins: opportunities and challenges. In: Smales CM, James DC (eds) Methods in molecular biology. Therapeutic proteins: methods and protocols, vol 308. Humana Press, Inc., Totowa, NJ, pp 1–16

3. Trill JJ, Shatzman AR, Ganguly S (1995) Production of monoclonal antibodies in COS and CHO cells. Curr Opin Biotechnol 6:553–560

4. Hacker DL, De Jesus M, Wurm FM (2009) 25 years of recombinant proteins from reactor-grown cells—where do we go from here? Biotechnol Adv 27:1023–1027

5. DrugBank (2017) About DrugBank. https://www.drugbank.ca/about . Accessed 14 Nov 2017

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