Proteomic studies on anti-tumor agent ansamitocin P-3 producer Actinosynnema pretiosum in response to ammonium and isobutanol
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Bioengineering,Biotechnology
Link
http://link.springer.com/article/10.1007/s00449-017-1763-5/fulltext.html
Reference28 articles.
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2. Cassady JM, Chan KK, Floss HG, Leistner E (2004) Recent developments in the maytansinoid antitumor agents. Chem Pharm Bull 52:1–26
3. Yu TW, Bai LQ, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG (2002) The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. Proc Natl Acad Sci USA 99:7968–7973
4. Fan YX, Gao Y, Zhou J, Wei LJ, Chen J, Hua Q (2014) Process optimization with alternative carbon sources and modulation of secondary metabolism for enhanced ansamitocin P-3 production in Actinosynnema pretiosum. J Biotechnol 192:1–10
5. Fan YX, Zhao MJ, Wei LJ, Hu FX, Imanaka T, Bai LQ, Hua Q (2016) Enhancement of UDPG synthetic pathway improves ansamitocin production in Actinosynnem pretiosum. Appl Microbiol Biotechnol 100:2651–2662
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