Study of the mechanism for increased protein expression via transcription potency reduction of the selection marker-Reference-Cited by-同舟云学术

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Study of the mechanism for increased protein expression via transcription potency reduction of the selection marker

Published:2019-02-07 Issue:5 Volume:42 Page:799-806
ISSN:1615-7591
Container-title:Bioprocess and Biosystems Engineering
language:en
Short-container-title:Bioprocess Biosyst Eng

Author:

Yang Bin,Zhou Jiatao,Zhao Hui,Wang Anling,Lei Yuanjun,Xie Qiuling,Xiong Sheng

Funder

Guangzhou Industry-Academia-Research Collaborative Innovation Project

Guangdong Provincial Science & Tech Project

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Bioengineering,Biotechnology

Link

http://link.springer.com/article/10.1007/s00449-019-02083-z/fulltext.html

Reference36 articles.

1. Matsuyama R, Yamano N, Kawamura N, Omasa T (2017) Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1. J Biosci Bioeng 123(3):382–389. https://doi.org/10.1016/j.jbiosc.2016.09.006

2. Deschenes I, Finkle CD, Winocour PD (1998) Effective use of BCH-2763, a new potent injectable direct thrombin inhibitor, in combination with tissue plasminogen activator (tPA) in a rat arterial thrombolysis model. Thromb Haemost 80(1):186–191

3. Walsh G (2010) Biopharmaceutical benchmarks 2010. Nat Biotechnol 28(9):917–924. https://doi.org/10.1038/nbt0910-917

4. Chu L, Robinson DK (2001) Industrial choices for protein production by large-scale cell culture. Curr Opin Biotechnol 12(2):180–187

5. Zhu J (2012) Mammalian cell protein expression for biopharmaceutical production. Biotechnol Adv 30(5):1158–1170. https://doi.org/10.1016/j.biotechadv.2011.08.022

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Weak promoters to drive selection marker expression: Improvement of cell line development process for therapeutic protein production in CHO-K1 cells;Journal of Biotechnology;2023-06

2. Enhanced Transgene Expression by Optimization of Poly A in Transfected CHO Cells;Frontiers in Bioengineering and Biotechnology;2022-01-24

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