Molecular docking analysis reveals differential binding affinities of multiple classes of selective inhibitors towards cancer-associated KRAS mutants-Reference-Cited by-同舟云学术

Molecular docking analysis reveals differential binding affinities of multiple classes of selective inhibitors towards cancer-associated KRAS mutants

Published:2022-11-06 Issue:12 Volume:12 Page:
ISSN:2190-572X
Container-title:3 Biotech
language:en
Short-container-title:3 Biotech

Author:

Mullaguri Sai Charitha^ORCID,Akula Sravani^ORCID,Sahoo Partha Sarathi^ORCID,Ashireddygari Vigneshwar Reddy^ORCID,Mupparapu Vyshnavika^ORCID,Silveri Ravalika^ORCID,Prasad Burra V. L. S.^ORCID,Kancha Rama Krishna^ORCID

Funder

Indian Council of Medical Research

DST-PURSE

Publisher

Springer Science and Business Media LLC

Subject

Agricultural and Biological Sciences (miscellaneous),Environmental Science (miscellaneous),Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s13205-022-03407-9.pdf

Reference21 articles.

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4. Fell JB, Fischer JP, Baer BR, Blake JF, Bouhana K, Briere DM, Brown KD, Burgess LE, Burns AC, Burkard MR, Chiang H, Chicarelli MJ, Cook AW, Gaudino JJ, Hallin J, Hanson L, Hartley DP, Hicken EJ, Hingorani GP, Hinklin RJ, Mejia MJ, Olson P, Otten JN, Rhodes SP, Rodriguez ME, Savechenkov P, Smith DJ, Sudhakar N, Sullivan FX, Tang TP, Vigers GP, Wollenberg L, Christensen JG, Marx MA (2020) Identification of the clinical development candidate MRTX849, a Covalent KRASG12C inhibitor for the treatment of cancer. J Med Chem 63:6679–6693. https://doi.org/10.1021/acs.jmedchem.9b02052

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