Separation of closely related monoclonal antibody charge variant impurities using poly(ethylenimine)-grafted cation-exchange chromatography resin
Author:
Publisher
Springer Science and Business Media LLC
Subject
Agricultural and Biological Sciences (miscellaneous),Environmental Science (miscellaneous),Biotechnology
Link
https://link.springer.com/content/pdf/10.1007/s13205-022-03350-9.pdf
Reference34 articles.
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3. Di Donato A, Ciardiello MA, de Nigris M, Piccoli R, Mazzarella L, D’Alessio G (1993) Selective deamidation of ribonuclease A. Isolation and characterization of the resulting Isoaspartyl and aspartyl derivatives. J Biol Chem 268:4745–4751
4. Ecker DM, Jones SD, Levine HL (2015) The therapeutic monoclonal antibody market. Mabs 7:9–14
5. Fernandes JC (2018) Therapeutic application of antibody fragments in autoimmune diseases: Current state and prospects. Drug Discov Today 23:1996–2002
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