Piezoelectric Transformer-Based High-Voltage Pulse Generator Using Wide-Bandgap Semiconductors for Medical Electroporation Therapy-Reference-Cited by-同舟云学术

Piezoelectric Transformer-Based High-Voltage Pulse Generator Using Wide-Bandgap Semiconductors for Medical Electroporation Therapy

Published:2023-07-19 Issue: Volume: Page:
ISSN:0090-6964
Container-title:Annals of Biomedical Engineering
language:en
Short-container-title:Ann Biomed Eng

Author:

Chole Ajay M.^ORCID,Duffy Maeve

Abstract

AbstractIn this paper, a new application of Piezoelectric Transformer (PT)-based power converters to generate high-voltage (HV) bipolar pulses for medical electroporation therapy is proposed. In particular, PT-based power conversion is investigated as an alternative to magnetics-based approaches of generating HV from a relatively low-voltage (LV) input source for application in electroporation therapy. The detailed PT-based system design and selection of wide bandgap semiconductor switches such as GaN FETs, high-voltage SiC diodes and SiC MOSFETs, as well as simulation results to demonstrate proof-of-concept using LTSpice are presented. Preliminary experimental results of the PT-based capacitor charger are shown, and work is ongoing to develop a complete hardware prototype of the proposed HV pulse generator.

Funder

College of Engineering and Informatics, National University of Ireland, Galway

National University Ireland, Galway

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering

Link

https://link.springer.com/content/pdf/10.1007/s10439-023-03319-6.pdf

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