Synthesis of praziquantel derivatives and theirin vitro activity against adultClonorchis sinensis

Author:

Kim Choong Sup,Min Duk Young

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Drug Discovery,Molecular Medicine

Reference10 articles.

1. Abo-Ghalia, M. H. and Soliman, A. E-M., Synthesis and antischistosomal activity of a new 2-nicotinoyl dipeptide analog of praziquantel.Arzneim.-Forsch., 46, 207–209 (1996).

2. Day, T. A., Bennett, J. L. and Pax, R. L., Praziquantel: the enigmatic antiparasitic.Parasitol. Today, 8, 342–344 (1992).

3. Frehel, D. and Maffrand, J-P., New syntheses of Praziquantel: 2-(cyclohexylcabonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-alisoquinolin-4-one.Heterocycles, 20, 1731–1735 (1983).

4. Hardman, J. G., Limbard, L. E., Molinoff, P. B., Ruddon, R. W. and Gilman, A. G.,Goodman & Gilman’s The Phamarcological Basis of Therapeutics, Intl. Ed., McGraw-Hill, New York, pp 1020–1022, (1996).

5. Hassanein, H., El Nahal, H. M. and Gerges, F. R., Synthesis of some non-antimonia compounds bioisosteric to praziquantel.Eur. J. Med. Chem. 30, 525–529 (1995).

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