Antibodies as Drug Carriers III: Design of Oligonucleotides with Enhanced Binding Affinity for Immunoglobulin G

Author:

Palma Enzo,Klapper David G.,Cho M. J.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Reference20 articles.

1. 1. A. F. Carpentier, G. Auf, and J.-Y. Delattre. CpG-Oligonucleotides for cancer immunotherapy: review of the literature and potential applications in malignant glioma. Front. Biosci. 8:115?127 (2003).

2. 2. P. Sazani and R. Kole. Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing. J. Clin. Invest. 112:481?486 (2003).

3. 3. S. Agrawal, J. Temsamani, W. Galbraith, and J. Tang. Pharmacokinetics of antisense oligonucleotides. Clin. Pharmacokinet. 28: 7?16 (1995).

4. 4. S. T. Crooke, M. J. Graham, J. E. Zuckerman, D. Brooks, B. S. Conklin, L. L. Cummins, M. J. Greig, C. J. Guinosso, D. Kornbrust, M. Manoharan, H. M. Sasmor, T. Schleich, K. L. Tivel, and R. H. Griffey. Pharmacokinetic properties of several oligonucleotide analogs in mice. J. Pharmacol. Exp. Ther. 277:923?937 (1996).

5. 5. G. Burdick and W. Emlen. Effect of antibody excess on the size, stoichiometry, and DNAse resistance of DNA anti-DNA immune complexes. J. Immunol. 135:2593?2597 (1985).

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