Drug Disposition Classification Systems in Discovery and Development: A Comparative Review of the BDDCS, ECCS and ECCCS Concepts-Reference-Cited by-同舟云学术

Drug Disposition Classification Systems in Discovery and Development: A Comparative Review of the BDDCS, ECCS and ECCCS Concepts

Published:2016-07-20 Issue:11 Volume:33 Page:2583-2593
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Camenisch Gian P.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s11095-016-2001-6.pdf

Reference31 articles.

1. Wu CY, Benet LZ. Predicting drug disposition via application of BCS: transport/absorption/elimination interplay and development of a Biopharmaceutics Drug Disposition Classification System. Pharm Res. 2005;22:11–23.

2. Benet LZ. The role of BCS (Biopharmaceutics Classification System) and BDDCS (Biopharmaceutics Drug Dispostion Classification Systen) in Drug Development. J Pharm Sci. 2013;102:34–42.

3. Camenisch G, Umehara K. Predicting human hepatic clearance from in vitro drug metabolism and transport data: a scientific and pharmaceutical perspective for assessing drug-drug interactions. Biopharm Drug Dispos. 2012;33:179–94.

4. Kunze A, Huwyler J, Poller B, Gutmann H, Camenisch G. In vitro-in vivo extrapolation method to predict human renal clearance of drugs. J Pharm Sci. 2014;103:994–1001.

5. Kunze A, Poller B, Huwyler J, Camenisch G. Application of the extended clearance concept classification system (EC3S) to predict the victim drug-drug interaction potential of statins. Drug Metab Pers Ther. 2015;30:175–88.

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