QSAR Modeling of the Blood–Brain Barrier Permeability for Diverse Organic Compounds-Reference-Cited by-同舟云学术

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QSAR Modeling of the Blood–Brain Barrier Permeability for Diverse Organic Compounds

Published:2008-06-14 Issue:8 Volume:25 Page:1902-1914
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Zhang Liying,Zhu Hao,Oprea Tudor I.,Golbraikh Alexander,Tropsha Alexander

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s11095-008-9609-0.pdf

Reference73 articles.

1. P. L. Golden, and G. M. Pollack. Blood–brain barrier efflux transport. J. Pharm. Sci. 92:1739–1753 (2003).

2. U. Bickel, T. Yoshikawa, and W. M. Pardridge. Delivery of peptides and proteins through the blood–brain barrier. Adv. Drug Deliv. Rev. 46:247–279 (2001).

3. C. L. Graff, and G. M. Pollack. Drug transport at the blood–brain barrier and the choroid plexus. Curr. Drug Metab. 5:95–108 (2004).

4. R. C. Young, R. C. Mitchell, T. H. Brown, C. R. Ganellin, R. Griffiths, M. Jones, K. K. Rana, D. Saunders, I. R. Smith, N. E. Sore, and T. J. Wilks. Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists. J. Med. Chem. 31:656–671 (1988).

5. M. H. Abraham, H. S. Chadha, and R. C. Mitchell. Hydrogen bonding. 33. Factors that influence the distribution of solutes between blood and brain. J. Pharm. Sci. 83:1257–1268 (1994).

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