Improving the Manufacturability of Cohesive and Poorly Compactable API for Direct Compression of Mini-tablets at High Drug Loading via Particle Engineering
Author:
Funder
Biogen
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology
Link
https://link.springer.com/content/pdf/10.1007/s11095-022-03413-9.pdf
Reference35 articles.
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2. Chen H, Wang C, Liu S, Sun CC. Development of piroxicam mini-tablets enabled by spherical cocrystallization. Int J Pharm. 2020;590: 119953.
3. Tissen C, Woertz K, Breitkreutz J, Kleinebudde P. Development of mini-tablets with 1mm and 2mm diameter. Int J Pharm. 2011;416(1):164–70.
4. Cho C-H, Kim J-Y, Park E-S. Effects of process parameters of rotary tablet press on die filling behavior during mini-tablet production: Comparison with conventional tablet. Powder Technol. 2020;362:90–100.
5. Mitra B, Chang J, Wu SJ, Wolfe CN, Ternik RL, Gunter TZ, Victor MC. Feasibility of mini-tablets as a flexible drug delivery tool. Int J Pharm. 2017;525(1):149–59.
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