Safety, Stability and Pharmacokinetic Properties of superFactor Va, a Novel Engineered Coagulation Factor V for Treatment of Severe Bleeding
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s11095-016-1895-3.pdf
Reference38 articles.
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2. von Drygalski A, Cramer TJ, Bhat V, Griffin JH, Gale AJ, Mosnier LO. Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant. J Thromb Haemost. 2014;12(3):363–72.
3. Mann KG, Jenny RJ, Krishnaswamy S. Cofactor proteins in the assembly and expression of blood clotting enzyme complexes. Annu Rev Biochem. 1988;57:915–56.
4. Schlachterman A, Schuettrumpf J, Liu JH, Freguia CF, Toso R, Poncz M, et al. Factor V Leiden improves in vivo hemostasis in murine hemophilia models. J Thromb Haemost. 2005;3(12):2730–7.
5. Franchini M, Lippi G. Factor V Leiden and hemophilia. Thromb Res. 2010;125(2):119–23.
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