Molecular Dynamics Simulations and Experimental Results Provide Insight into Clinical Performance Differences between Sandimmune® and Neoral® Lipid-Based Formulations
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology
Link
https://link.springer.com/content/pdf/10.1007/s11095-021-03099-5.pdf
Reference65 articles.
1. Williams HD, Trevaskis NL, Charman SA, Shanker RM, Charman WN, Pouton CW, Porter CJH. Strategies to address low drug solubility in discovery and development. Pharmacol Rev. 2013;65(1):315–499.
2. Pouton CW. Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system. Eur J Pharm Sci. 2006;29(3–4):278–87.
3. Benson SP, Pleiss J. Molecular dynamics simulations of self-emulsifying drug-delivery systems (SEDDS): influence of excipients on droplet nanostructure and drug localization. Langmuir. 2014;30(28):8471–80.
4. Birru WA, Warren DB, Han S, Benameur H, Porter CJH, Pouton CW, Chalmers DK. Computational models of the gastrointestinal environment. 2. Phase behavior and drug Solubilization capacity of a type I lipid-based drug formulation after digestion. Mol Pharm. 2017;14(3):580–92.
5. Kasimova AO, Pavan GM, Danani A, Mondon K, Cristiani A, Scapozza L, Gurny R, Möller M. Validation of a novel molecular dynamics simulation approach for lipophilic drug incorporation into polymer micelles. J Phys Chem B. 2012;116(14):4338–45.
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. 1-Benzhydryl-piperazine: Isolation, structure determination, and in silico studies for a novel potential narcotic agent detected in sports supplements;Journal of Food Composition and Analysis;2024-11
2. Accelerating Formulation Design via Machine Learning: Generating a High-throughput Shampoo Formulations Dataset;Scientific Data;2024-07-03
3. Artificial Intelligence and Machine Learning in Pharmacokinetics and Pharmacodynamic Studies;Pharmacokinetics and Pharmacodynamics of Novel Drug Delivery Systems: From Basic Concepts to Applications;2024
4. Synthesis and Anticancer Activity of Novel Derivatives of α,β‐Unsaturated Ketones Based on Oleanolic Acid: in Vitro and in Silico Studies against Prostate Cancer Cells;Chemistry & Biodiversity;2023-09
5. Leveraging the use of in vitro and computational methods to support the development of enabling oral drug products: An InPharma commentary;European Journal of Pharmaceutical Sciences;2023-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3