Rapid-Acting and Human Insulins: Hexamer Dissociation Kinetics upon Dilution of the Pharmaceutical Formulation-Reference-Cited by-同舟云学术

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Rapid-Acting and Human Insulins: Hexamer Dissociation Kinetics upon Dilution of the Pharmaceutical Formulation

Published:2017-07-31 Issue:11 Volume:34 Page:2270-2286
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Gast Klaus,Schüler Anja,Wolff Martin,Thalhammer Anja,Berchtold Harald,Nagel Norbert,Lenherr Gudrun,Hauck Gerrit,Seckler Robert

Funder

Sanofi-Aventis Deutschland GmbH

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

http://link.springer.com/article/10.1007/s11095-017-2233-0/fulltext.html

Reference36 articles.

1. Zaykov AN, Mayer JP, DiMarchi RD. Pursuit of a perfect insulin. Nat Rev Drug Discov. 2016;15(6):425–39.

2. Brange J, Owens DR, Kang S, Vølund A. Monomeric insulins and their experimental and clinical implications. Diabetes Care. 1990;13(9):923–54.

3. Jeffrey PD, Coates JH. An equilibrium ultracentrifuge study of the self-association of bovine insulin. Biochemistry. 1966;5(2):489–98.

4. Pekar AH, Frank BH. Conformation of proinsulin. A comparison of insulin and proinsulin self-association at neutral pH. Biochemistry. 1972;11(22):4013–6.

5. Goldman J, Carpenter FH. Zinc binding, circular dichroism, and equilibrium sedimentation studies on insulin (bovine) and several of its derivatives. Biochemistry. 1974;13(22):4566–74.

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