Potential Oral Delivery of 7-Ethyl-10-Hydroxy-Camptothecin (SN-38) using Poly(amidoamine) Dendrimers

Author:

Kolhatkar Rohit B.,Swaan Peter,Ghandehari Hamidreza

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Reference28 articles.

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3. P. J. Houghton, P. J. Cheshire, J. C. Hallman, M. C. Bissery, A. Mathieu-Boue, and J. A. Houghton. Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against human tumor xenografts: lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor 9-dimethylaminomethyl-10-hydroxycamptothecin. Cancer Res. 53:2823–2829 (1993).

4. P. Calabresi, B. A. Chabner, J. G. Hardman, and L. E. Limbird. Chemotherapy of Neoplastic Diseases, Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 10McGraw-Hill (Medical Publishing Division), New York, 2001, p. 1424.

5. H. Ulukan, M. T. Muller, and P. W. Swaan. Downregulation of topoisomerase I in differentiating human intestinal epithelial cells. Int. J. Cancer. 94:200–207 (2001).

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