Commonly Used Excipients Modulate UDP-Glucuronosyltransferase 2B7 Activity to Improve Nalbuphine Oral Bioavailability in Humans-Reference-Cited by-同舟云学术

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Commonly Used Excipients Modulate UDP-Glucuronosyltransferase 2B7 Activity to Improve Nalbuphine Oral Bioavailability in Humans

Published:2014-02-14 Issue:7 Volume:31 Page:1676-1688
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Wang Hong-Jaan,Hsiong Cheng-Huei,Ho Shung-Tai,Lin Min-Jen,Shih Tung-Yuan,Huang Pei-Wei,Hu Oliver Yoa-Pu

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s11095-013-1272-4.pdf

Reference39 articles.

1. Kalasz H, Antal I. Drug excipients. Curr Med Chem. 2006;13:2535–63.

2. Chen ML. Lipid excipients and delivery systems for pharmaceutical development: a regulatory perspective. Adv Drug Deliv Rev. 2008;60(6):768–77.

3. Buggins TR, Dickinson PA, Taylor G. The effects of pharmaceutical excipients on drug disposition. Adv Drug Deliv Rev. 2007;59(15):1482–503.

4. Wandel C, Kim RB, Stein CM. “Inactive” excipients such as Cremophor can affect in vivo drug disposition. Clin Pharmacol Ther. 2003;73(5):394–6.

5. Bravo González RC, Huwyler J, Boess F, Walter I, Bittner B. In vitro investigation on the impact of the surface-active excipients Cremophor EL, Tween 80 and Solutol HS 15 on the metabolism of midazolam. Biopharm Drug Dispos. 2004;25(1):37–49.

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