In Vitro Regional Deposition of Nasal Sprays in an Idealized Nasal Inlet: Comparison with In Vivo Gamma Scintigraphy

Author:

Chen John Z.,Finlay Warren H.,Martin Andrew

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Reference36 articles.

1. Pharmacopiea U. Aerosols, nasal sprays, metered-dose inhalers, and dry powder inhalers. US Pharmacopeial [Internet]. 2006;30:2617–36. Available from: http://www.pharmacopeia.cn/v29240/usp29nf24s0_c601_viewall.html

2. U.S. Department of Health and Human Services, Food and Drug Administration Center for Drug Evaluation and Research D of DI (HFD-240). Draft: Guidance for Industry Bioavailability and Bioequivalence Studies for Nasal Aerosol and Nasal Sprays for Local Action. 2003; Available from: http://www.fda.gov/cder/guidance/index.htm

3. Newman SP, Pitcairn GR, Dalby RN. Drug Delivery to the Nasal Cavity: In Vitro and In Vivo Assessment. Critical Reviews in Therapeutic Drug Carrier Systems. 2004;21:46.

4. Li Bv, Jin F, Lee SL, Bai T, Chowdhury, Badrul Caramenico HT, Conner DP. Bioequivalence for locally acting nasal spray and nasal aerosol products: Standard development and generic approval. The AAPS Journal. 2013;15:875–83.

5. Below A, Bickmann D, Breitkreutz J. Assessing the performance of two dry powder inhalers in preschool children using an idealized pediatric upper airway model. International Journal of Pharmaceutics. Elsevier B.V.; 2013;444:169–74.

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