Understanding the Role of Preferential Exclusion of Sugars and Polyols from Native State IgG1 Monoclonal Antibodies and its Effect on Aggregation and Reversible Self-Association
Author:
Funder
MedImmune LLC
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s11095-019-2642-3.pdf
Reference45 articles.
1. Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS. Stability of protein pharmaceuticals: an update. Pharm Res. 2010;27(4):544–75.
2. Elgundi Z, Reslan M, Cruz E, Sifniotis V, Kayser V. The state-of-play and future of antibody therapeutics. Adv Drug Deliv Rev. 2017;122:2–19.
3. Ratanji KD, Derrick JP, Dearman RJ, Kimber I. Immunogenicity of therapeutic proteins: influence of aggregation. J Immunotoxicol. 2014;11(2):99–109.
4. Raut AS, Kalonia DS. Pharmaceutical perspective on opalescence and liquid-liquid phase separation in protein solutions. Mol Pharm. 2016;13(5):1431–44.
5. Yang Y, Velayudhan A, Thornhill NF, Farid SS. Multi-criteria manufacturability indices for ranking high-concentration monoclonal antibody formulations. Biotechnol Bioeng. 2017;114(9):2043–56.
Cited by 33 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. On the role of excipients in biopharmaceuticals manufacture: Modelling-guided formulation identifies the protective effect of arginine hydrochloride excipient on spray-dried Olipudase alfa recombinant protein;International Journal of Pharmaceutics;2024-09
2. Investigation on environmental factors contributing to bispecific antibody stability and the reversal of self-associated aggregates;Bioresources and Bioprocessing;2024-08-23
3. Stability of Protein Pharmaceuticals: Recent Advances;Pharmaceutical Research;2024-06-27
4. A Structural Study on Absorption of Lysozyme in Amorphous Starch Microspheres;Molecular Pharmaceutics;2024-05-13
5. The Development of a Novel Aflibercept Formulation for Ocular Delivery;Journal of Pharmaceutical Sciences;2024-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3