Abstract
AbstractThe full characteristic of the crystallization process of aripiprazole crystal is given. Our research reveals that a degree of crystallinity calculated from the analyses of data of light intensity passing through the sample (Thermo-Optical Analysis based on Polarized Light Microscopy—POM), the Canny edge detection algorithm, and Differential Scanning Calorimetry—DSC, are in good agreement. The parameters of Avrami model, the dimensionality of the crystal growth, and the characteristic crystallization temperature, obtained from POM and DSC methods coincide. The obtained values of the Avrami exponent n suggest that the crystal growth is three-dimensional.
Publisher
Springer Science and Business Media LLC
Subject
Physical and Theoretical Chemistry,Condensed Matter Physics,Polymers and Plastics,Materials Chemistry