DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver
Author:
Funder
National Institute on Aging
Publisher
Springer Science and Business Media LLC
Subject
Geriatrics and Gerontology,Ageing
Link
http://link.springer.com/content/pdf/10.1007/s11357-020-00181-5.pdf
Reference68 articles.
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3. Barzilai N, Huffman DM, Muzumdar RH, Bartke A. The critical role of metabolic pathways in aging. Diabetes. 2012;61:1315–22. https://doi.org/10.2337/db11-1300.
4. Benayoun BA, Pollina EA, Brunet A. Epigenetic regulation of ageing: linking environmental inputs to genomic stability. Nat Rev Mol Cell Biol. 2015;16:593–610. https://doi.org/10.1038/nrm4048.
5. Bonder MJ, Kasela S, Kals M, Tamm R, Lokk K, Barragan I, et al. Genetic and epigenetic regulation of gene expression in fetal and adult human livers. BMC Genomics. 2014;15:860. https://doi.org/10.1186/1471-2164-15-860.
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