Methylation of CpG sites in BCL2 major breakpoint region and the increase of BCL2/JH translocation with aging-Reference-Cited by-同舟云学术

Methylation of CpG sites in BCL2 major breakpoint region and the increase of BCL2/JH translocation with aging

Published:2015-09-03 Issue:5 Volume:37 Page:
ISSN:0161-9152
Container-title:AGE
language:en
Short-container-title:AGE

Author:

Martin-Guerrero Idoia,de Prado Elena,Ardanaz Maite,Martin-Arruti Maialen,Garcia-Orad Cristina,Guerra Isabel,Ruiz Irune,Zabalza Iñaki,Garcia-Orad Africa

Publisher

Springer Science and Business Media LLC

Subject

Geriatrics and Gerontology,Ageing,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s11357-015-9834-5.pdf

Reference17 articles.

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2. Bakhshi A, Wright JJ, Graninger W, Seto M, Owens J, Cossman J, Jensen JP, Goldman P, Korsmeyer SJ (1987) Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners. Proc Natl Acad Sci U S A 84(8):2396–2400

3. Cleary ML, Sklar J (1985) Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci U S A 82(21):7439–7443

4. Cui X, Lu Z, Kurosawa A, Klemm L, Bagshaw AT, Tsai AG, Gemmell N, Müschen M, Adachi N, Hsieh CL, Lieber MR (2013) Both CpG methylation and activation-induced deaminase are required for the fragility of the human bcl-2 major breakpoint region: implications for the timing of the breaks in the t(14;18) translocation. Mol Cell Biol 33(5):947–957

5. Heyn H, Li N, Ferreira HJ, Moran S, Pisano DG, Gomez A, Diez J, Sanchez-Mut JV, Setien F, Carmona FJ, Puca AA, Sayols S, Pujana MA, Serra-Musach J, Iglesias-Platas I, Formiga F, Fernandez AF, Fraga MF, Heath SC, Valencia A, Gut IG, Wang J, Esteller M (2012) Distinct DNA methylomes of newborns and centenarians. Proc Natl Acad Sci U S A 109(26):10522–10527