Cannabinoids in Symptomatic Treatment for People with Multiple Sclerosis: a Systematic Review of Randomised Studies-Reference-Cited by-同舟云学术

Cannabinoids in Symptomatic Treatment for People with Multiple Sclerosis: a Systematic Review of Randomised Studies

Published:2023-07-18 Issue:3 Volume:11 Page:303-312
ISSN:2167-4833
Container-title:Current Physical Medicine and Rehabilitation Reports
language:en
Short-container-title:Curr Phys Med Rehabil Rep

Author:

Filippini Graziella^ORCID,Minozzi Silvia,Borrelli Francesca,Cinquini Michela,Dwan Kerry

Publisher

Springer Science and Business Media LLC

Subject

Rehabilitation,Physical Therapy, Sports Therapy and Rehabilitation,Orthopedics and Sports Medicine,Medicine (miscellaneous)

Link

https://link.springer.com/content/pdf/10.1007/s40141-023-00416-4.pdf

Reference38 articles.

1. Hazekamp A, Ware MA, Muller-Vahl KR, Abrams D, Grotenhermen F. The medicinal use of cannabis and cannabinoids–an international cross-sectional survey on administration forms. J Psychoactive Drugs. 2013;45(3):199–210.

2. MS Society. Cannabis and MS. Available at https://www.mssociety.org.uk/about-ms/treatments-and-therapies/complementary-and-alternative-therapies/cannabis. Accessed 19 Mar 2023.

3. Mecha M, Yanguas-Casás N, Feliú A, Mestre L, Carrillo-Salinas F, Azcoitia I, et al. The endocannabinoid 2-AG enhances spontaneous remyelination by targeting microglia. Brain, Behav Immun. 2019;77:110–26.

4. Gonçalves ED, Dutra RC. Cannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand? Drug Discov Today. 2019;24(9):1845–53.

5. • Furgiuele A, Cosentino M, Ferrari M, Marino F. Immunomodulatory potential of cannabidiol in multiple sclerosis: a systematic review. J Neuroimmune Pharmacol. 2021;16(2):251–69. This systematic review reports that evidence in rodent models of experimental autoimmune encephalomyelitis strongly supports cannabidiol as effective, while highlights clinical evidence is still limited, due to paucity of studies and possibly to the use of suboptimal dosing regimens.