Antitumor activity and cross-resistance of carmethizole hydrochloride in preclinical models in mice

Author:

Waud William R.,Plowman Jacqueline,Harrison Steadman D.,Dykes Donald J.,Anderson Wayne K.,Griswold Daniel P.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference20 articles.

1. Anderson WK, Bhattacharjee D, Houston DM, Plowman J, Harrison SD Jr (1988) Design, preparation, chemical properties and antitumor activity of carmethizole hydrochloride. Proc Am Assoc Cancer Res 29: 326

2. Anderson WK, Bhattacharjee D, Houston DM (1989) Design, synthesis, antineoplastic activity, and chemical properties of bis(carbamate) derivatives of 4,5-bis(hydroxymethyl)imidazole. J Med Chem 32: 119

3. Brockman RW (1974) Mechanisms of resistance. In: Sartorelli AC, Johns DG (eds) Handbook of experimental pharmacology, new series, vol 38/1. Springer, New York Berlin Heidelberg, p 352

4. Brodfuehrer JI, Wilke TJ, Kinder DH, Powis G (1989) Preclinical pharmacologic studies of the new antitumor agent carmethizole (NSC-602 668) in the mouse and beagle dog. Cancer Chemother Pharmacol 24: 277

5. Carney DN, Gazdar AF, Bepler G, Guccion JG, Marangos PJ, Moody TW, Zweig MH, Minna JD (1985) Establishment and identification of small cell lung cancer cell lines having classic and variant features. Cancer Res 45: 2913

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