An initial slope method for model structure: Independent estimation of the elimination rate constant of a metabolite-Reference-Cited by-同舟云学术

An initial slope method for model structure: Independent estimation of the elimination rate constant of a metabolite

Published:1991-06 Issue:3 Volume:19 Page:311-318
ISSN:0090-466X
Container-title:Journal of Pharmacokinetics and Biopharmaceutics
language:en
Short-container-title:Journal of Pharmacokinetics and Biopharmaceutics

Author:

Piotrovskii Vladimir K.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Link

http://link.springer.com/content/pdf/10.1007/BF03036253.pdf

Reference8 articles.

1. K. K. Chan. A simple integrated method for drug and derived metabolite kinetics. An application of the statistical moment theory.Drug Metab. Dispos. 10:474–479 (1982).

2. H. Cheng and W. J. Jusko. An area function method for calculating the apparent elimination rate constant of a metabolite.J. Pharmacokin. Biopharm. 17:125–130 (1989).

3. V. K. Piotrovskii. Model-independent definition of the initial volume of distribution of drugs in the body.Int. J. Clin. Pharmacol. Ther. Toxicol. 24:403–407 (1986).

4. M. Gibaldi and D. Perrier.Pharmacokinetics, 2nd ed., Marcel Dekker, New York, 1982.

5. K. S. Pang and J. R. Gillette. Metabolite pharmacokinetics: methods for simultaneous estimates of elimination rate constants of a drug and its metabolite.Drug Metab. Dispos. 8:39–43 (1980).

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