Cardiac and coronary vasodilator profile of pimobendan, a new cardiotonic drug, revealed by use of isolated, blood-perfused dog heart preparations

Author:

Imagawa Jun-ichi,Satoh Keisuke,Taira Norio

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine

Reference24 articles.

1. Diederen W, Dämmgen J, Kadatz R (1982) Cardiovascular profile of UD-CG 115, a new orally and long acting cardiotonic compound, not related toβ-mimetics or cardiac glycosides. Naunyn Schmiedebergs Arch Pharmacol 321: R36

2. Honerjäger P, Heiss A, Schäfer-Korting M, Schönsteiner G, Reiter M (1984) UD-CG 115—a cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle. Naunyn Schmiedebergs Arch Pharmacol 325: 259–269

3. Berger C, Meyer W, Scholz H, Starbatty J (1985) Effects of the benzimidazole derivatives pimobendan and 2-(4-hydroxyphenyl)-5-(5-methyl-3-oxo-4,5-dihydro-2H-6-pyridazinyl) benzimidazole·HCl on phosphodiesterase activity and force of contraction in guinea-pig hearts. Arzneimittelforsch 35: 1668–1673

4. Van Meel JCA (1985) Cardiovascular effects of the positive inotropic agents pimobendan and sulmazole in vivo. Arzneimittelforsch 35: 284–288

5. Duncker DJ, van Dalen FJ, Hartog JM, Lamers JMJ, Rensen RJ Saxena PR, Verdouw PD (1986) Usefulness of pimobendan in the treatment of heart failure. Arzneimittelforsch 36: 1740–1744

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