Synthesis and evaluation of some novel N-substituted rhodanines for their anticancer activity

Author:

Ali Muhammad Sulaiman,Ravi Subban,Thangamani Arumugam

Funder

Department of Science and Technology (DST-SERB)

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Reference30 articles.

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2. Alizadeh A, Rostamnia S, Zohreh N, Hosseinpour R (2009) A simple and effective approach to the synthesis of rhodanine derivatives via three-component reactions in water. Tetrahedron Lett 50:1533–1535

3. Anumala UR, Gu J, Monte FL, Kramer T, Haußen RB, Hölzer J, Goetschy-Meyer V, Schön C, Mall G, Hilger I, Czech C, Herms J, Schmidt B (2013) Fluorescent rhodanine-3-acetic acids visualize neurofibrillary tangles in Alzheimer’s disease brains. Bioorg Med Chem 21:5139–5144

4. Arung ET, Wicaksono BD, Handoko YA, Kusuma IW, Yulia D, Ferrry S (2009) Anti- cancer properties of diethylether extract of wood from sukun (artocarpus altilis) in human breast cancer (T47D) cells). J Immunol Methods 8:217–324

5. Bernardo PH, Xu J, Wan KF, Sivaraman T, Krishnamurthy J, Mok HYK, Yu VC, Chai CLL (2009) Rhodanine-based Pan-Bcl-2 inhibitors and Mcl-1-specific inhibitors as anti-cancer compounds (WO 2010024783). International Patent no (PCT/SG2009/000301)

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