Design, synthesis, and LFA-1/ICAM-1 antagonist activity evaluation of Lifitegrast analogues
Author:
Funder
Technology Program of Liaoning
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s00044-022-02851-9.pdf
Reference34 articles.
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2. Rouen PA, White ML. Dry eye disease: prevalence, assessment, and management. Home Healthc Now. 2018;36:74–83. https://doi.org/10.1097/NHH.0000000000000652.
3. Pult H, Purslow C, Murphy P. The relationship between clinical signs and dry eye symptoms. Eye. 2011;25:502–10. https://doi.org/10.1038/eye.2010.228.
4. Potvin R, Makari S, Rapuano CJ. Tear film osmolarity and dry eye disease: a review of the literature. Clin Ophthalmol. 2015;9:2039–47. https://doi.org/10.2147/OPTH.S95242.
5. Marlin SD, Springer TA. Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Cell. 1987;51:813–9. https://doi.org/10.1016/0092-8674(87)90104-8.
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2. An Improved Synthetic Process of Two Key Intermediates and Their Application in the Synthesis of Lifitegrast;Pharmaceutical Fronts;2023-08-03
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