2D-QSAR of purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells

Author:

Singh Supriya,Saxena Anil K.

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Reference11 articles.

1. Callery P, Gannett P (2002) Cancer and Cancer Chemotherapy, In Foye’s Principles of Medicinal Chemistry, Lippincott Williams and Wilkins Philadelphia: pp 925

2. Chiosis G,Lucas B, Shtil A, Huezo H, Rosen N (2002) Development of a Purine Scaffold Novel Class of Hsp90 Binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 Tyrosine Kinase. Bioorg Med Chem 10:3555–3564

3. Dymock B, Barril X, Beswick M, Collier A, Davies N, Drysdale M, Fink A, Fromont C, Hubbard RE, Massey A, Surgenor A, Wright L (2004) Adenine derived inhibitors of the molecular chaperone Hsp90 - SAR explained through multiple X- ray structures. Bioorg Med Chem 14:325–328

4. Hansch C, Leo A (1979) Substituent Constants for Correlation Analysis in Chemistry and Biology. Wiley Interscience, New York, p. 48

5. Hansch C,Leo A, Hoekman D (1995) Exploring QSAR: Hydrophobic, Electronic and Steric Constants. Am Chem Soc 2:1

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