Role of the Caco-2 cell culture model developed in Dr. Ronald T. Borchardt’s lab in modern drug research and development: a perspective from a practitioner
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Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00044-024-03266-4.pdf
Reference38 articles.
1. Hidalgo IJ, Raub TJ, Borchardt RT. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology. 1989;96:736–49.
2. Hu M, Borchardt RT. Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2). Pharm Res. 1990;7:1313–9. https://doi.org/10.1023/a:1015906409585.
3. Hu M, Borchardt RT. Transport of a large neutral amino acid in a human intestinal epithelial cell line (Caco-2): uptake and efflux of phenylalanine. Biochim Biophys Acta. 1992;1135:233–44. https://doi.org/10.1016/0167-4889(92)90226-2.
4. Borchardt RT, Hidalgo IJ, Raub TJ, Borchardt RT. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability, gastroenterology, 96, 736–749, 1989–the backstory. AAPS J. 2011;13:323–7. https://doi.org/10.1208/s12248-011-9283-8.
5. Brayden DJ. Per Artursson’s major contributions to the Caco-2 cell literature in pharmaceutical sciences. J Pharm Sci. 2021;110:12–6. https://doi.org/10.1016/j.xphs.2020.08.016.
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