Stable isotope applications in drug development and the elucidation of mechanisms of drug metabolism
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s00044-023-03142-7.pdf
Reference35 articles.
1. Baillie TA. The use of stable isotopes in pharmacological research. Pharmacol Rev. 1981;33:81–132.
2. Haskins NJ. The application of stable isotopes in biomedical research. Biomed Mass Spectrom. 1982;9:269–77. https://doi.org/10.1002/bms.1200090702.
3. Ortiz de Montellano P. Substrate oxidation. Cytochrome P450: Structure, Mechanism, and Biochemistry. New York: Springer; 2015.
4. Guengerich FP. Kinetic Deuterium Isotope effects in Cytochrome P450 reactions. Methods Enzymol. 2017;596:217–38.https://doi.org/10.1016/bs.mie.2017.06.036.
5. K Johnson, H Le, SC Khojasteh, S Ma, and SK Chowdhury, Chapter 15 - The use of stable isotopes in drug metabolism studies,” in Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters 2nd ed. Amsterdam: Elsevier, 2020, p. 439–460.
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