Synthesis, antitumor activities and functional mechanism of purine derivatives harboring phenyl moieties through three carbon bridges
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s00044-023-03038-6.pdf
Reference36 articles.
1. Michael F. Folate, DNA damage and the aging brain. Mech Aging Dev. 2010;131:236–41.
2. Gangjee A, Zeng YB, McGuire JJ, Kisliuk RL. Synthesis of N-[4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid as an antifolate. J Med Chem. 2005;48:5329–36.
3. Gubner R, August S, Ginsberg V. Therapeutic suppression of tissue reactivity. II. effect of aminopterin in rheumatoid arthritis and psoriasis. Am J Med Sci. 1951;221:176–82.
4. Gangjee A, Jain HD, Phan J, Lin X, Song XH, McGuire JJ, et al. Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates. J Med Chem. 2006;49:1055–65.
5. Gonen N, Assaraf YG. Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance. Drug Resist Updat. 2012;15:183–10.
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