Synthesis of fluorene and/or benzophenone O-oxime ethers containing amino acid residues and study of their cardiovascular and antibacterial effects

Author:

Soltani Rad Mohammad Navid,Behrouz Somayeh,Zarenezhad Elham,Moslemin Mohammad Hossein,Zarenezhad Ali,Mardkhoshnood Mehdi,Behrouz Marzieh,Rostami Saeid

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Reference37 articles.

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2. Balsamo A, Breschi MC, Chiellini G, Macchia B, Macchia M, Manera C, Saccà P, Scatizzi R (1996) New chiral methyloxyiminomethyl (MOIM) β-adrenergic antagonists. (S)- and (R)-N-[3-(alkylamino)-2-hydroxypropylidene](p-chlorophenylmethyloxy)amines as probes for determining enantiomeric specificity in the class of MOIM-type β-adrenergic blocking agents. Eur J Med Chem 31:199–206. doi: 10.1016/0223-5234(96)89135-5

3. Balsamo A, Breschi MC, Chiellini G, Lapucci A, Lazzeri N, Macchia M, Martinelli A, Micali E, Nencetti S, Rossello A (1998) Synthesis and beta-adrenergic properties of (Z)-N-[3-(alkylamino)-2-hydroxypropylidene](aryl-methyloxy)amines: effects of the configuration around the methyloxyiminomethyl (MOIM) double bond on the biopharmacological properties of MOIM-type beta-blocking agents. Bioorg Med Chem 6:2151–2160. doi: 10.1016/S0968-0896(98)00172-2

4. Balsamo A, Macchia M, Martinelli A, Rossello A (1999) The [(methyloxy)imino]methyl moiety (MOIMM) in the design of a new type of β-adrenergic blocking agent. Eur J Med Chem 34:283–291. doi: 10.1016/S0223-5234(99)80079-8

5. Breschi MC, Macchia M, Manera C, Micali E, Nardini C, Nencetti S, Rossello A, Scatizzi R (1996) Conformationally restrained β-blocking oxime ethers. 3. Synthesis and β-adrenergic antagonistic activity of diastereomeric anti and syn 2-(5′-(3′-methyl)isoxazolidinyl)-N-alkylethanolamines. Eur J Med Chem 31:159–163. doi: 10.1016/0223-5234(96)80449-1

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