Design, synthesis, and evaluation of potential carbamate prodrugs of 5′-methylthioadenosine (MTA)
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s00044-021-02730-9.pdf
Reference23 articles.
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2. Avila MAA, Garcı́a-Trevijano ER, Lu SC, Corrales FJ, Mato JM. Methylthioadenosine. Int J Biochem Cell Biol. 2004;36:2125–30. https://doi.org/10.1016/j.biocel.2003.11.016.
3. Lubin M, Lubin A. Selective Killing of Tumors Deficient in Methylthioadenosine Phosphorylase: a Novel Strategy. PLoS ONE. 2009;4:e5735. https://doi.org/10.1371/journal.pone.0005735.
4. Tang B, Testa JR, Kruger WD. Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells. Cancer Biol Ther. 2012;13:1082–90. https://doi.org/10.4161/cbt.21115.
5. Bertino JR, Waud WR, Parker WB, Lubin M. Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies. Cancer Biol Ther. 2011;11:627–32. https://doi.org/10.4161/cbt.11.7.14948.
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