Synthesis of benzothiazole derivatives and their biological evaluation as anticancer agents-Reference-Cited by-同舟云学术

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Synthesis of benzothiazole derivatives and their biological evaluation as anticancer agents

Published:2011-09-10 Issue:9 Volume:21 Page:2644-2651
ISSN:1054-2523
Container-title:Medicinal Chemistry Research
language:en
Short-container-title:Med Chem Res

Author:

Caputo Rosanna,Calabrò Maria Luisa,Micale Nicola,Schimmer Aaron D.,Ali Moshin,Zappalà Maria,Grasso Silvana

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Link

http://link.springer.com/content/pdf/10.1007/s00044-011-9789-8.pdf

Reference16 articles.

1. Aiello S, Wells G, Stone EL, Kadri H, Bazzi R, Bell DR, Stevens MFG, Matthews CS, Bradshaw TD, Westwell AD (2008) Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). J Med Chem 51:5135–5139

2. Boyd MR (1997) Preclinical screening, clinical trials, and approval. Humana Press, Totowa, NJ

3. Boyd MR, Paull KD (1995) Some practical considerations and applications of the national cancer institute in vitro anticancer drug discovery screen. Drug Dev Res 34:91–109

4. Brantley E, Antony S, Kohlhagen G, Meng LH, Agama K, Stinson SF, Sausville EA, Pommier Y (2006) Anti-tumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces single-strand breaks and DNA-protein cross-links in sensitive MCF-7 breast cancer cells. Cancer Chemother Pharmacol 58:62–72

5. Das J, Moquin RV, Lin J, Liu C, Doweyko AM, DeFex HF, Fang Q, Pang S, Pitt S, Shen DR, Schieven GL, Barrish JC, Wityak J (2003) Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors. Bioorg Med Chem Lett 13:2587–2590

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