Synthesis, molecular docking, and apoptogenic efficacy of novel N-heterocycle analogs to target B-cell lymphoma 2/X-linked inhibitors of apoptosis proteins to regress melanoma-Reference-Cited by-同舟云学术

Synthesis, molecular docking, and apoptogenic efficacy of novel N-heterocycle analogs to target B-cell lymphoma 2/X-linked inhibitors of apoptosis proteins to regress melanoma

Published:2019-06-04 Issue:8 Volume:28 Page:1132-1160
ISSN:1054-2523
Container-title:Medicinal Chemistry Research
language:en
Short-container-title:Med Chem Res

Author:

Zabiulla Zabiulla,Malojirao Vikas H.,Mohammed Yasser Hussein Eissa,Thirusangu Prabhu,Prabhakar B. T.,Khanum Shaukath Ara

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Link

http://link.springer.com/content/pdf/10.1007/s00044-019-02357-x.pdf

Reference38 articles.

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2. Al-Ghorbani M, Thirusangu P, Gurupadaswamy HD, Girish V, Neralagundi HGN, Prabhakar BT, Khanum SA (2016) Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton’s lymphoma. Bioorg Chem 65:73–81

3. Balasubramanyam K, Altaf M, Radhika AV, Swaminathan V, Aarthi R, Parag P, Sadhal Kundu TP (2004) Polyisoprenylated benzophenone, garcinol, a natural HAT inhibitor represses chromatin transcription and alters global gene expression. J Biol Chem 279:33716–33726

4. Eberle J, Hossini AM (2008) Expression and function of Bcl-2 proteins in melanoma. Curr Genomics 9:409–419

5. Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35:495–516

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