The effect of ara-C-induced inhibition of DNA synthesis on its cellular pharmacology

Author:

Wang Li-Ming,Courtland White J.,Capizzi Robert L.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference27 articles.

1. Capizzi RL, Powell BL (1987) Sequential high dose ara-C and asparaginase versus high dose ara-C alone in the treatment of patients with relapsed and refractory acute leukemias. Semin Oncol 14 [Suppl 1]:40

2. Capizzi RL, Papirmeister B, Mullins JM, Cheng E (1974) The detection of chemical mutagens using the L5178Y/asn murine leukemia in vitro and in a host-mediated assay. Cancer Res 34:3073

3. Capizzi RL, Yang JL, Cheng E, Bjornsson T, Sahasrabudhe D, Tan RS, Cheng YC (1983) Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U, in patients with acute leukemia. J Clin Oncol 1:763

4. Capizzi RL, Oliver L, Friedman H, Davis R, Mayer R, Schiffer C, Lunghofer B, Royer G, Van Echo DA (1988) Variations in ara-C plasma concentration at steady-state during remission induction and intensification therapy of AML. A population pharmacokinetic study by CALGB. Proc Am Soc Clin Oncol 7:57

5. Eriksson S, Thelander L, Akerman M (1979) Allosteric regulation of calf thymus ribonucleoside diphosphate reductase. Biochemistry 18:2948

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