Wann sollte eine Methotrexat-Hepatopathie vermutet werden und welche Maßnahmen sind sinnvoll?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
https://link.springer.com/content/pdf/10.1007/s00393-021-01136-7.pdf
Reference13 articles.
1. Baggott JE, Vaughn WH, Hudson BB (1986) Inhibition of 5‑aminoimidazole4-carboxamide ribotide transformylase, adenosine deaminase and 5’-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5‑aminoimidazole-4-carboxamide riboside and ribotide. Biochem J 236(1):193–200
2. Chan ES, Montesinos MC, Fernandez P et al (2006) Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis. Br J Pharmacol 148(8):1144–1155
3. Kaplowitz N, DeLeve LD (2013) Drug-induced liver disease, 3. Aufl. Elsevier, London
4. Salliot C, van der Heijde D (1993) Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research. Ann Rheum Dis 68(7):1100–1104
5. Conway R, Low C, Coughlan RJ, O’Donnell MJ, Carey JJ (2015) Risk of liver injury among methotrexate users: a meta-analysis of randomised controlled trials. Semin Arthritis Rheum 45(2):156–162
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