TYMS polymorphisms and responsiveness to or toxicity of methotrexate in rheumatoid arthritis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://link.springer.com/article/10.1007/s00393-018-0419-4/fulltext.html
Reference33 articles.
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2. Banerjee D, Mayer-Kuckuk P, Capiaux G et al (2002) Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase. Biochim Biophys Acta 1587(2–3):164–173
3. Bohanec Grabar P, Logar D, Lestan B et al (2008) Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism. Eur J Clin Pharmacol 64(11):1057–1068
4. Borman P, Tasbas O, Karabulut H et al (2015) Thymidylate synthase genetic polymorphism and plasma total homocysteine level in a group of Turkish patients with rheumatoid arthritis: relationship with disease activity and methotrexate toxicity. Rev Bras Reumatol. https://doi.org/10.1016/j.rbr.2014.12.001
5. Chaabane S, Marzouk S, Akrout R et al (2015) Genetic Determinants of Methotrexate Toxicity in Tunisian Patients with Rheumatoid Arthritis: A Study of Polymorphisms Involved in the MTX Metabolic Pathway. Eur J Drug Metab Pharmacokinet. https://doi.org/10.1007/s13318-015-0288-z
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