Intravesical Botulinum Toxin for Neurogenic Bladder—Can We Just Irrigate the Bladder with Botulinumtoxin?

Author:

Aisen Carrie Mlynarczyk,Chung Doreen E.

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Biochemistry

Reference31 articles.

1. Gormley EA, Lightner DJ, Faraday M, Vasavada SP. Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guideline amendment. J Urol. 2015;193(5):1572–80.

2. Allergan. BOTOX® (ONABOTULINUMTOXINA) Receives U.S. FDA Approval for the treatment of urinary incontinence in adults with neurological conditions including multiple sclerosis and spinal cord injury. News Release. 2011.

3. BOTOX® injections can provide long-lasting bladder control for patients with neurogenic bladder [press release]. 2011.

4. Nitti VW. Botulinum toxin for the treatment of idiopathic and neurogenic overactive bladder: state of the art. Reviews in urology. 2006;8(4):198–208.

5. • Moore DC, Cohn JA, Dmochowski RR. Use of botulinum toxin A in the treatment of lower urinary tract disorders: a review of the literature. Toxins. 2016;8(4):88. This paper gives a comprehensive background review on the use of BTX-A intradetrusor injections for the treatment of lower urinary tract disorders. It provides an excellent explanation of the mechanism of BTX-A and a review of relevant studies.

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