Urinary Biomarkers and Benign Prostatic Hyperplasia

Author:

Tyagi Pradeep,Wang Zhou,Yoshimura Naoki

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Biochemistry

Reference104 articles.

1. • Yoo S, Oh S, Park J, Cho SY, Cho MC, Jeong H, et al. The impacts of metabolic syndrome and lifestyle on the prevalence of benign prostatic hyperplasia requiring treatment: historical cohort study of 130 454 men. BJU Int. 2018;123(1):140–8. https://doi.org/10.1111/bju.14528 . Important epidemiological study demonstrating the influence of obesity on BPH.

2. • Oelke M, Wagg A, Takita Y, Buttner H, Viktrup L. Efficacy and safety of tadalafil 5 mg once daily in the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia in men aged ≥75 years: integrated analyses of pooled data from multinational, randomized, placebo-controlled clinical studies. BJU Int. 2017;119(5):793–803. https://doi.org/10.1111/bju.13744 . Important study on the medical treatment of storage symptoms in BPH patients.

3. • Vella M, Abrate A, Costanzo A, D'Amato F, Tarantino ML, Simonato A. Predictive variables of spontaneous micturition recovery after acute urinary retention in men with benign prostatic enlargement: an observational prospective study. Lower urinary tract symptoms. 2018. Doi: https://doi.org/10.1111/luts.12241 . Important study identifying the predictors of treatment response.

4. •• Nickel JC, Roehrborn CG, Castro-Santamaria R, Freedland SJ, Moreira DM. Chronic prostate inflammation is associated with severity and progression of benign prostatic hyperplasia, lower urinary tract symptoms and risk of acute urinary retention. J Urol. 2016;196(5):1493–8. https://doi.org/10.1016/j.juro.2016.06.090 . Important study implicating the role of prostatic inflammation in incidence of acute urinary retention and BPH/LUTS.

5. Torkko KC, Wilson RS, Smith EE, Kusek JW, van Bokhoven A, Lucia MS. Prostate biopsy markers of inflammation are associated with risk of clinical progression of benign prostatic hyperplasia: findings from the MTOPS study. J Urol. 2015;194(2):454–61. https://doi.org/10.1016/j.juro.2015.03.103 .

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