Immunomodulation by orally administered protein-bound polysaccharide PSK in patients with gastrointestinal cancer

Author:

Nio Yoshinori,Tsubono Michihiko,Tseng Chen-Chiu,Morimoto Hideki,Kawabata Kazuya,Masai Yoshikazu,Shiraishi Takahiro,Imai Shiro,Ohgaki Kazuhisa,Tobe Takayoshi

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference25 articles.

1. Akiyama J, Kawamura T, Gotohda E, Yamada Y, Hosokawa M, Kodama T, Kobayashi H. Immunochemotherapy of transplanted KMT-17 tumor in WKA rats by combination of cyclophosphamide and immunostimulatory protein-bound polysaccharide isolated from basidiomycetes. Cancer Res 1977; 37: 3042–5.

2. Ebina T, Kohya H, Yamaguchi T, Ishida N. Antimetastatic effect of biological response modifiers in the "double grafted tumor system". Jpn J Cancer Res (Gann) 1986; 77: 1034–42.

3. Ebina T, Kohya H. Antitumor effector mechanism at a distant site in the double grafted tumor system of PSK, a protein-bound polysaccharide preparation. Jpn J Cancer Res (Gann) 1988; 79: 957–64.

4. Ernest PB, Schicchitano R, Underdown BJ, Bienenstock J. Oral immunization and tolerance. In: Heyworth MF, Jones AI, eds. Immunology of the gastrointestinal tract and liver. New York: Raven Press Ltd., 1988: 125–44.

5. Ehlike MJ, Reino JM, Eppolito C, Mihich E. The effect of PS-K, a protein bound polysaccharide, an immune responses against allogenic antigens. Int J Immunopharmac 1983; 5: 35–42.

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